---
title: "悟空云数据分析交流第二期之组缺失值填充NAGuideR工具"
author: "omicsolution"
account: "omicsolution"
published_at: "2020-08-21T11:01:29+08:00"
captured_at: "2026-08-24T11:50:16.862017+08:00"
source_url: "https://mp.weixin.qq.com/s?__biz=MzI2MTI5NDAzNg==&mid=100000998&idx=1&sn=41441fb3e4a8ccfbf8da6674c9cbddeb&chksm=6a5dd65d5d2a5f4b2a051ff49166a8930dada2dd578a8bc4137544bac41406bf5e6e3fe39a51#rd"
---

# 悟空云数据分析交流第二期之组缺失值填充NAGuideR工具
在过去的七月份我们联合复旦大学生物医学研究院举办了面向新生的蛋白质组学全套入门培训，参与人数近300人，通过回收的考卷发现大部分考核学员超过80%正确率，初步实现了我们的培训预期。

我们将陆续为广大老师同学提供更加深入的培训内容。

在6月份进行了悟空云数据分析交流_第一期之后，我们邀请诗盛为其刚发布的：悟空云4周年，Nucleic Acids Research发表NAguideR缺失值填充评价工具进行专场演示和讲解，为大家更好地熟悉和使用该工具提供便利。如需进一步交流学习欢迎加入悟空交流QQ群：688728477 现在已经有600多个小伙伴加入啦，也可以点击阅读原文访问悟空云。

对悟空云平台还不熟悉的小伙伴们也可以单独学习我们7月份培训班中悟空的专题培训内容：

目前基于悟空平台开发的分析工具已发表以下文章：

NAguideR模块：

(2020) Shisheng Wang , Wenxue Li, Liqiang Hu, Jingqiu Cheng, Hao Yang, Yansheng Liu, NAguideR: performing and prioritizing missing value imputations for consistent bottom-up proteomic analyses, Nucleic Acids Research, gkaa498. (IF: 11).

motifeR模块：

(2019) Shisheng Wang , Yue Cai, Jingqiu Cheng, Wenxue Li, Yansheng Liu and Hao Yang. motifeR: An Integrated Web Software for Identification and Visualization of Protein Post‐Translational Modification Motifs. Proteomics: 201900245. (IF: 3).

pseudoQC模块：

(2019) Shisheng Wang and Hao Yang. pseudoQC: A Regression‐Based Simulation Software for Correction and Normalization of Complex Metabolomics and Proteomics Datasets. Proteomics: 1900264. (IF: 3).

MetaboGroupS模块：

(2018) Shisheng Wang , ..., and Meng Gong. MetaboGroupS: A Group Entropy-Based Web Platform for Evaluating Normalization Methods in Blood Metabolomics Data from Maintenance Hemodialysis Patients. Anal Chem 90, 11124-11130. (IF: 6).

MixProTool模块：

(2018) Shisheng Wang , ..., and Hao Yang. MixProTool: A Powerful and Comprehensive Web Tool for Analyzing and Visualizing Multigroup Proteomics Data. Journal of computational biology : a journal of computational molecular cell biology 25, 1123-1127. (IF: 1).

![图片 1](images/001.png)

同时悟空平台整合上百个分析模块，包括且远不止以下功能

![图片 2](images/002.png)

而围绕上游质谱数据解析和下游组学应用，易算近期也发表了多篇文章：

(2020)Yi Yang, ..., and Liang Qiao In silico spectral libraries by deep learning facilitate data-independent acquisition proteomics. Nature Communications

https://doi.org/10.1038/s41467-019-13866-z (IF:13)

(2020）Shuping Long, ..., Liang Qiao Metaproteomics characterizes human gut microbiome function in colorectal cancer. npj Biofilms and Microbiomes

https://doi.org/10.1038/s41522-020-0123-4 (IF: 18)

(2020) Rutan Zhang, ..., Liang Qiao Proteomic and Metabolic Elucidation of Solar-Powered Biomanufacturing by Bio-Abiotic Hybrid System.

https://doi.org/10.1016/j.chempr.2019.11.002 (IF:5)

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