[Update 11.3.221103.47784]
- Added calibration curve linear fit descriptors
- Disabling clustering when there is not enough data points
[Update 11.2.221014.47784]
- Removed multiplexed information in Thermo QExactive instrument method output
- Allow deselection of "Show Legend" in MS1/MS2 Alignment plots
[Update 11.1.220930.47784]
- Added -command option to command-line interface
大版本升级[SpectroDive 11 - Release Notes]
New Absolute Quantification Workflow
- Creation and visualization of calibration curves
- Determination of limits of detection (LOD) and of quantification (LLOQ, ULOQ)
- Quantification of samples using calibration curves
Ion Mobility Support
- FAIMS-PRM: analysis and method export
- prm-PASEF: analysis and method export
Support for New Acquisition Methods
- Hybrid-DIA: analysis and method export for targeted peptides
Improved Performance
- Improved peak picking
- Improved Pulsar search engine for panel generation
Improved User Experience and Visualization
- Improved XIC Alignment plots with support for unlimited number of runs
- Detachable perspective and plots for side-by-side visualization
- Improved XIC grid overview plots
- One-Click tree navigation in plots
- Improved plot and tree filter selection
- Quick-Action bar for analysis perspective
- Improved UI for analysis log
- New prm-PASEF mobilogram plot
- Streamlined settings for clarity with new advanced category
- Switched to a 2-color system for identification status annotation
[Update 10.7.220414.47784]
- Added saved experiment SPE saving from CLI
- Allow loading a settings schmema from name or file path in CLI
- Implemented quantity correction from samples conditions setup
[Update 10.6.220225.47784]
- Calculating number of removed assays in MRM
- Automatic upgrade and/or warning to save to new SPE file standard
[Update 10.5.211227.47784]
- Added scores for library fragments in refinement window
- Consistent date/time format for iRT calibration runs
[Update 10.3.210226.47784]
- Significant improvement in RAM requirement
- Changed default strategy for summarizing multiple survey runs by taking an average across peptide, instead of lowest
- Updated manual
[Update 10.2.210120.47784]
- Clean up of temporary files was not happening after closing a SureQuant experiment
- Improved loading performance for search archives using Pulsar for library generation
- Added unpaired t-test strategy and made it default for regulation analysis
- Improved fall back tolerances if automatic mass calibration did not have enough data points
- New default option for spike-in workfow which requires identification of both target and reference channels
大版本升级[SpectroDive 10 - Release Notes]
Full Support for SureQuant Analysis
- Support for method development for custom panels
- Seamless data analysis with optimized peak picking for SureQuant acquisition
- Post Analysis plots specifically for SureQuant acquisition
Improved False Discovery Rate Analysis
- New decoy strategy for PRM and SureQuant
- Reliable and automatic FDR for MRM, PRM and SureQuant analysis
Improved Performance
- SpectroDive uses up to 30% less RAM than before
Library based PRM Scheduling
- Import iRT calibration directly from a DDA or DIA spectral library for scheduling
- Support for non-linear gradients
Improved Panel Support
- Improved support for panel generation from library
- Improved support for modifying an existing panel
- Support for refining assays directly from a targeted analysis
- Improved GUI for refining iRT and fragment selection
Library Generation
- View library settings in library perspective (for new libraries only)
- Improved identifications from deep learning augmented scoring with Pulsar
- Added PD 2.4 support
Other Features
- New global settings for setting up SureQuant acquisition from a survey run
- Mono-isotopic MS1 quantity is now reported for PRM and SureQuant
- SpectroDive Viewer is available for browsing of already analyzed experiments
- Various minor improvements in user experience
[Update 9.10.190923.41419]
- Added interference score for transitions in the report perspective
[Update 9.6.190725.41419]
- Added skip to last option for external panel import in prepare perspective to easily import panel as it is
[Update 9.5.190416.41419]
- Added support for fill time correction in multipexed PRM
[Update 9.1.190401.41419]
- Added ability to sort runs by different criterias such as acqusition date, condition, etc.
大版本升级What is new in SpectroDive 9.0?
- Improved panel generation workflow starting from spectral library
- Support for non-linear gradient based inclusion list scheduling
- Support for DDA or DIA based inclusion list scheduling
- Improved PRM data analysis by using MS1 information
- Pulsar database search engine integration
- PQ500 human plasma panel support
- MaxQuant.Live support
- Improved wizard based experiment setup
- Improved performance and memory management
[Bug Fixes 8.0.14288.5]
- Switched to new MassLynxRawSDK API for Waters MRM data
[Bug Fixes 8.0.14288.4]
- Improved scaling for mirrored XIC chart in alignment view
[Bug Fixes 8.0.14288.3]
- Added support to specify panel when setting up an experiment from command line prompt
[Bug Fixes 8.0.14288.1]
- Added support for Xcalibur 4.0 method export
- Added support for Fusion PRM
大版本升级What is new in SpectroDive 8.0?
- Library generation from DDA results
- MRM / PRM panel generation from library
- Fragment ion refinement for PRM panels
- Improved performance for PRM
- Improved memory management
- Improved cache management
- Improved performance for loading / saving SPE files
- On-Click integration in XIC plots
- Data-completeness plot in post analysis
- CVs below X plot in post analysis
- Experiment overview grid in post analysis
- MS2 scan at apex plot for PRM
- Improved workflow for mixed analysis (MRM and PRM)
- Improved modification management
- Improved UI scalability
[Update 7.5.10300.4]
- Improved panel matching
- Minor bug fixes and improvements
大版本升级[Release Notes]What is new in SpectroDive 7.5?
- Support for Agilent instruments
- Improved performance for PRM workflows
- iRT refinement for PRM panels
- Miscellaneous minor bug fixes and improvements