1. 新增第二版画火山图模块（相比较第一版，这里的阈值界线为曲线，相比较直线，曲线是经过校正得到，具体可参考文献：DOI, 10.1002/pmic.201600132.用户可以通过调节经验系数和置信区间对曲线进行调整。）：
2. 新增差异分析limma模块（该模块主要使用limma函数包进行differential expression analysis）：
3. 新增两表格关联模块（此模块可方便用户根据一个表格的内容，从另外一个表格中提取出对应的信息）：
4. 优化从整个fasta文件中批量提取蛋白质的序列模块（新增统计序列氨基酸的个数结果，方便用户参看整合）：
5. 优化假设检验模块（优化多组时求倍数变化组别识别出错的问题）：
6. 优化变异系数计算模块（优化下载变异系数分布图时报错的问题）：
7. 优化画带圈的散点图模块（修复勾掉置信椭圆参数时依然显示置信椭圆的问题）：
8. 优化String网络分析模块（由于官网更新，相关旧链接不能使用，更新后可正常分析作图）：
(2020) Shisheng Wang , Wenxue Li, Liqiang Hu, Jingqiu Cheng, Hao Yang, Yansheng Liu, NAguideR: performing and prioritizing missing value imputations for consistent bottom-up proteomic analyses, Nucleic Acids Research, gkaa498. (IF: 11). (2019) Shisheng Wang , Yue Cai, Jingqiu Cheng, Wenxue Li, Yansheng Liu and Hao Yang. motifeR: An Integrated Web Software for Identification and Visualization of Protein Post‐Translational Modification Motifs. Proteomics: 201900245. (IF: 3). (2019) Shisheng Wang and Hao Yang. pseudoQC: A Regression‐Based Simulation Software for Correction and Normalization of Complex Metabolomics and Proteomics Datasets. Proteomics: 1900264. (IF: 3). (2018) Shisheng Wang , ..., and Meng Gong. MetaboGroupS: A Group Entropy-Based Web Platform for Evaluating Normalization Methods in Blood Metabolomics Data from Maintenance Hemodialysis Patients. Anal Chem 90, 11124-11130. (IF: 6). (2018) Shisheng Wang , ..., and Hao Yang. MixProTool: A Powerful and Comprehensive Web Tool for Analyzing and Visualizing Multigroup Proteomics Data. Journal of computational biology : a journal of computational molecular cell biology 25, 1123-1127. (IF: 1). 同时悟空平台整合上百个分析模块，包括且远不止以下功能而围绕上游质谱数据解析和下游组学应用，易算近期也发表了多篇文章：(2020)Yi Yang, ..., and Liang Qiao In silico spectral libraries by deep learning facilitate data-independent acquisition proteomics. Nature Communicationshttps://doi.org/10.1038/s41467-019-13866-z (IF:13) (2020）Shuping Long, ..., Liang Qiao Metaproteomics characterizes human gut microbiome function in colorectal cancer. npj Biofilms and Microbiomes https://doi.org/10.1038/s41522-020-0123-4 (IF: 18)(2020) Rutan Zhang, ..., Liang Qiao Proteomic and Metabolic Elucidation of Solar-Powered Biomanufacturing by Bio-Abiotic Hybrid System. https://doi.org/10.1016/j.chempr.2019.11.002 (IF:5)marketing@omicsolution.com
